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52:44 Agnieszka Borowska (Glasgow): Gaussian process… Agnieszka Borowska (Glasgow): Gaussian process enhanced semi-automatic approximate Bayesian computation: parameter inference in a stochastic differential equation system for chemotaxis	Agnieszka Borowska (Glasgow): Gaussian process enhanced semi-automatic approximate Bayesian computation: parameter inference in a stochastic differential equation system for chemotaxis Agnieszka Borowska (Glasgow): Gaussian process enhanced semi-automatic approximate Bayesian computation: parameter inference in a stochastic differential equation system for chemotaxis Chemotaxis is… statistics research parameters cell parameter abc regression features estimates model outputs points element point membrane process simulator step cases nodes instance distribution From OLLIE Quinn on February 4th, 2021 0 likes 11 plays 0 Licence Type All rights reserved Language English Date Created January 29th, 2021
17:49 Pharmacology 3: Drugs Acting on Ion Channels Part… Pharmacology 3: Drugs Acting on Ion Channels Part 4 Dr Phil Larkman	Pharmacology 3: Drugs Acting on Ion Channels Part 4 Dr Phil Larkman Modulation of Na+ channels by local anaesthetics. channel sodium anesthetic anesthetics channels block ph ion alanine charge drugs pathway form membrane permeability phenyl action drug point mutation From Philip Larkman on October 30th, 2020 0 likes 106 plays 0 Licence Type Creative Commons - Attribution
08:48 Pharmacology 3: Drugs Acting on Ion Channels Part… Pharmacology 3: Drugs Acting on Ion Channels Part 3 Dr Phil Larkman	Pharmacology 3: Drugs Acting on Ion Channels Part 3 Dr Phil Larkman Modulation of voltage-gated Na+ channels by tetrodotoxin tetrodotoxin sodium channel channels voltage filter selectivity potassium molecule fish heart position water ion moiety puffer glutamate 3a4 side membrane From Philip Larkman on October 29th, 2020 0 likes 103 plays 0 Licence Type Creative Commons - Attribution
17:39 Pharmacology 3: Drugs Acting on Ion Channels Part… Pharmacology 3: Drugs Acting on Ion Channels Part 2 Dr Phil Larkman	Pharmacology 3: Drugs Acting on Ion Channels Part 2 Dr Phil Larkman Voltage-gated ion channel structure and function. channel voltage filter sodium potassium ions selectivity region amino structure panel residues sensor gate membrane channels ion activation transmembrane configuration From Philip Larkman on October 29th, 2020 1 likes 129 plays 0 Licence Type Creative Commons - Attribution
07:50 Pharmacology 3: Drugs Acting on Ion Channels … Pharmacology 3: Drugs Acting on Ion Channels Part 1 Dr Phil Larkman	Pharmacology 3: Drugs Acting on Ion Channels Part 1 Dr Phil Larkman Introduction - the importance of ion channels in cellular function. channels ion voltage channel sodium function action potassium cell cells calcium activation membrane potential mutations neurotransmitter drugs structure drug sensitivity From Philip Larkman on October 29th, 2020 0 likes 110 plays 0 Licence Type Creative Commons - Attribution
08:37 Medical Sciences 1: Pharmacokinetic Aspects of… Medical Sciences 1: Pharmacokinetic Aspects of General Anaesthesia Part 1 Dr Phil Larkman	Medical Sciences 1: Pharmacokinetic Aspects of General Anaesthesia Part 1 Dr Phil Larkman Inhalational anaesthetics - route of delivery and absorption blood anesthetic lungs anesthetics body barrier brain membrane inhalation pressure agents atrium place tissues oxygen routes concentration vessels effects hemoglobin From Philip Larkman on October 19th, 2020 0 likes 73 plays 0 Licence Type Creative Commons - Attribution
18:00 Medical Sciences 1: Mechanism of Action of… Medical Sciences 1: Mechanism of Action of General Anaesthetics Part 3 Dr Phil Larkman	Medical Sciences 1: Mechanism of Action of General Anaesthetics Part 3 Dr Phil Larkman Protein targets for GA action 2 channels potential potassium membrane channel effects anesthetic agents ion ketamine inhalation excitability anesthetics glutamate targets receptors receptor transmission inhibition equilibrium From Philip Larkman on October 18th, 2020 0 likes 58 plays 0 Licence Type Creative Commons - Attribution
13:13 Medical Sciences 1: Mechanism of Action of… Medical Sciences 1: Mechanism of Action of General Anaesthetics Part 1 Dr Phil Larkman	Medical Sciences 1: Mechanism of Action of General Anaesthetics Part 1 Dr Phil Larkman Lipid theory of GA action anesthetic brain effects images solubility agent agents hypothesis parts anesthetics targets actions evidence membrane drug concentration action cell theory lipid From Philip Larkman on October 18th, 2020 0 likes 82 plays 0 Licence Type Creative Commons - Attribution
11:40 BMS2: Chemical Synaptic Transmission 3 Part 3 Dr… BMS2: Chemical Synaptic Transmission 3 Part 3 Dr Phil Larkman	BMS2: Chemical Synaptic Transmission 3 Part 3 Dr Phil Larkman GPCR-mediated slow synaptic transmission potential receptors protein receptor acetylcholine inhibitory channels response duration events pathway signal mechanism activation potentials cells membrane beta potassium millivolts From Philip Larkman on October 15th, 2020 0 likes 232 plays 0 Licence Type Creative Commons - Attribution
14:44 BMS2: Chemical Synaptic Transmission 3 Part 2 Dr… BMS2: Chemical Synaptic Transmission 3 Part 2 Dr Phil Larkman	BMS2: Chemical Synaptic Transmission 3 Part 2 Dr Phil Larkman Muscarinic receptor modulation of cardiac and smooth muscle contraction calcium receptors muscle contraction channel acetylcholine heart receptor protein channels membrane beta potassium action guinea m2 kinase pig ion stores From Philip Larkman on October 15th, 2020 0 likes 258 plays 0 Licence Type Creative Commons - Attribution
10:45 BMS2: Chemical Synaptic Transmission 2 Part 3 Dr… BMS2: Chemical Synaptic Transmission 2 Part 3 Dr Phil Larkman	BMS2: Chemical Synaptic Transmission 2 Part 3 Dr Phil Larkman Pharmacology of the NMJ receptor acetylcholine receptors muscle junction antagonist action block drugs desensitization acetylcholinesterase contraction function agonist potential membrane depolarization drug effects pharmacology From Philip Larkman on October 14th, 2020 0 likes 247 plays 0 Licence Type Creative Commons - Attribution
25:23 BMS2 Chemical Synaptic Transmission 2 Part 2 Dr… BMS2 Chemical Synaptic Transmission 2 Part 2 Dr Phil Larkman	BMS2 Chemical Synaptic Transmission 2 Part 2 Dr Phil Larkman Ion permeability of the nACh receptor potential membrane sodium equilibrium ions channel potassium muscle calcium millivolts end acetylcholine channels plate ion flow receptor contraction action receptors From Philip Larkman on October 14th, 2020 0 likes 325 plays 0 Licence Type Creative Commons - Attribution
25:16 BMS2: Chemical Synaptic Transmission 1 Part 3 Dr… BMS2: Chemical Synaptic Transmission 1 Part 3 Dr Phil Larkman	BMS2: Chemical Synaptic Transmission 1 Part 3 Dr Phil Larkman Calcium-dependent release of acetylcholine calcium terminal potential membrane release size response process vesicle events vesicles action neurotransmitter neuron amplitude junction transmitter peroxidase proteins end From Philip Larkman on October 7th, 2020 0 likes 284 plays 0 Licence Type Creative Commons - Attribution
21:44 BMS2: Chemical Synaptic Transmission 1 Part 2 Dr… BMS2: Chemical Synaptic Transmission 1 Part 2 Dr Phil Larkman	BMS2: Chemical Synaptic Transmission 1 Part 2 Dr Phil Larkman Structure and function of the NMJ acetylcholine muscle potential motor neuron action acetylcholinesterase terminal neurotransmitter junction plate contraction membrane end transporter process toxin vesicles terminals inhibitors From Philip Larkman on October 7th, 2020 0 likes 323 plays 0 Licence Type Creative Commons - Attribution
20:12 BMS2: Chemical Synaptic Transmission 1 Part 1 Dr… BMS2: Chemical Synaptic Transmission 1 Part 1 Dr Phil Larkman	BMS2: Chemical Synaptic Transmission 1 Part 1 Dr Phil Larkman Principles of Chemical Transmission neurotransmitter chemical transmission neuron terminal synapse heart stimulation potential muscle release process evidence cells junction nerve motor membrane effect action From Philip Larkman on October 7th, 2020 0 likes 310 plays 0 Licence Type Creative Commons - Attribution
11:13 BMS2: How Drugs Act . Part 4 Dr Phil Larkman BMS2: How Drugs Act . Part 4 Dr Phil Larkman	BMS2: How Drugs Act . Part 4 Dr Phil Larkman Molecular insights into drug-receptor interactions drugs channel acetylcholine receptor cells ion targets sites drug binding channels action enzymes anesthetics membrane structure subunits transporters body voltage From Philip Larkman on September 28th, 2020 0 likes 324 plays 0 Licence Type All rights reserved The University of Edinburgh

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